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Clinically proven to combat ‘inflammaging.’
September 18, 2020
By: Charlie Sternberg
Associate Editor
Ultra in combination Bicosome, has launched Bicoalgae ω3 (Omega-3) in North America. Bicoalgae ω3 is a naturally based product that endogenously promotes the resolution of chronic inflammatory conditions that accelerates aging (inflammaging). It has been clinically proven for barrier function, melanin reduction and other disorders related to inflammaging. Bicoalgae ω3 is a natural origin delivery system with targeted delivery of two microalgae extracts rich in Omega-3 fatty acids. N. gaditana is a rich source of Omega-3 EPA and I. galbana of Omega-3 DHA. Bicoalgae ω3 has a double encapsulation which stabilizes the microalgae bioactives, helping to reduce common issues of discoloration or odor that can be seen with other marine-based ingredients. “Bicoalgae ω3 is produced with an innovative, eco-friendly, sustainable process,” said Jim Lynch, VP of Worldwide Sales. “This helps to protect aquatic ecosystems and avoids pollution & contamination.” Ex-vivo efficacy studies have been conducted showing the effectiveness of Bicoalgae ω3 for decreasing inflammatory cytokines IL- 1β and IL-8 as well as decreasing the oxidative stress as a result of exposure to blue light from electronic devices and UV-Vis. Bicoalgae ω3 decreased the level of the age-related pro-inflammatory cytokines IL-1β and IL-8 in inflamed skin by 97% and 59% respectively and decreased ROS up to 124%. The constant release of pro-inflammatory cytokines and ROS characterize chronic skin inflammation while a decrease of these markers in inflamed tissues indicate improvement of inflamed skin. Clinically Proven Results Further in vivo studies were conducted to evaluate the impact Bicoalgae ω3 has on conditions related to inflamed skin. Results showed an increase in skin barrier function, with a decrease in melanin reduction, sunspots, red spots and pores. Positive results were also seen after clinical evaluation, patient self-assessment and aesthetic evaluation of product in formulation.
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